Hydroxyapatite (abbreviated as HA or HAP) has a composition similar to that of natural apatite minerals and is the main inorganic component of vertebrate bones and teeth. Its structure is also very close, presenting a flaky microcrystalline state. It is used as a bone substitute in bone transplantation. HA has good biocompatibility. When implanted in the body, it is not only safe and non - toxic, but also can conduct bone growth. HA bioceramics are typical bioceramics. After being implanted in the body, they can form chemical - bond - like connections with tissues at the interface.

1) The product mainly corresponds to the orthopedic repair and medical aesthetics filling markets. According to the estimation in this report, as of 2020, the number of patients was 2.0243 million to 2.1508 million, among which the orthopedic field had the most patients, with 1.7031 million to 1.7238 million patients, and the demand for dental implants was 3.2753 million pieces.

2) Regarding the application of hydroxyapatite in stomatology, according to the data, in 2020, the amount of oral repair bone powder used in China was 2.01 million grams. It is expected that the market demand will reach 5.34 million grams by 2025. Assuming that the penetration rate of oral repair bone powder in dental implant surgery is 35% and will increase slightly to 36% in the next three years, and the price of oral repair bone powder is 1,400 yuan each time, it is calculated that the market space of oral repair bone powder is expected to reach 14.95 billion yuan by 2025.

3) The application of hydroxyapatite in medical aesthetics has just begun. With the product research and development entering the fast lane, the future product demand will have explosive growth. The efficacy of hydroxyapatite microspheres is better than that of "girl's needle" and "baby - face needle". It is estimated that the future market is expected to reach hundreds of billions.

The current market demand and clinical pain points are that the application of hydroxyapatite in the medical aesthetics field is still in its early stages, with no domestic products available. The price of hydroxyapatite in the international market is high, about 100,000 yuan per kilogram. The price is generally high, the supply channels are single, and the international situation is highly uncertain. After the product is industrialized, the raw material price will become one of the competitive advantages of future products. The domestic production of hydroxyapatite has become a rigid demand. Terminal enterprises, after choosing international market products, also need to choose domestic products at the same time as one of the core channels in the future, so as to increase the raw material sources of the product industry pipeline, fight against future uncertainties, optimize the product cost, and improve the comprehensive competitiveness of the product.

Hydroxyapatite bioceramic powder has a wide range of uses in medical implants. For example, when added to degradable fracture internal fixation materials, it can significantly reduce the acidic reaction during the degradation process of degradable polymers and at the same time increase the strength of degradable internal fixation; when thermally sprayed on the surface of metal materials, it can strengthen the osseous connection between the implanted prosthesis and the bone tissue, such as joint coatings and intervertebral disc fusion coatings; when used as bone defect repair materials, it can significantly enhance the bone conduction performance and thus play a role in bone repair.