Is hydroxyapatite (CaHA) bone meal? The answer is no, CaHA ≠ bone meal!

　　In the field of materials science, hydroxyapatite and bone meal are very different in size, composition and properties, although they are somewhat similar.

　　Hydroxyapatite (CaHA)

　　Hydroxyapatite for medical fillers, such as Jinzhi collagen microspheres, is composed primarily of 50% CaHA and 50% type I collagen. It has plasticizing, regenerating, filling and collagen direct replenishment and full-layer firming effects. This material has received dual certification from the Chinese NMPA Class III and the US FDA.

　　Bone meal material

　　Bone meal mainly contains calcium, phosphorus and other mineral components, and is usually used in agriculture as organic fertilizer to provide plants with the nutrients they need for growth, especially calcium and phosphorus, which help plants develop their root systems and enhance their resistance to falling.

　　Differences in appearance and size

　　Hydroxyapatite and bone meal differ in appearance and size. Jinzhi collagen microspheres are not bone meal.

　　Different physiological effects

　　Jinzhi collagen microspheres mainly stimulate collagen regeneration, mainly in the dermis and periosteum layer (particle size). Bone powder material mainly acts on bone defects, guiding/inducing bone tissue regeneration and restoring bone integrity.

　　Different degradation characteristics

　　Jinzhi collagen microspheres degrade slowly and metabolize naturally, and finally degrade into calcium and phosphate ions which are absorbed by the body and metabolized out of the body within about 1 year. On the other hand, bone powder material needs to maintain the stability of osteogenic space in the early stage, and needs to be degraded and metabolized slowly in the later stage. Currently, the degradation of bone powder materials is very slow.

　　Jinzhi collagen microsphere CaHA

　　CaHA is a biodegradable material with a 96+ year history of medical use and national regulatory approval. Jinzhi Collagen Microspheres are patented for mineralized collagen regeneration. Type I collagen extracted from the bovine Achilles tendon is used for direct collagen replenishment along the path of the CaHA microsphere pores. The stimulation of the microspheres causes the gradual differentiation of soft tissue cells towards fibroblasts, which are further stimulated to produce collagen scaffolds by the uptake of amino acids. the degradation of CaHA produces a large amount of calcium and phosphate ions, which gives it good adsorption properties, and the porous structure creates more adsorption space, and the newborn collagen will be produced more quickly and more abundantly.